org.simBio.bio.takeuchi_et_al_2006.current
Class PMCA
java.lang.Object
org.simBio.core.Component
org.simBio.core.Parameter
org.simBio.core.Composite
org.simBio.core.Reactor
org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter
org.simBio.bio.takeuchi_et_al_2006.current.PMCA
- All Implemented Interfaces:
- Node
public class PMCA
- extends MembraneTransporter
sarcolemmal Ca2+ pump.
The current amplitude is adjusted so that the contribution of PMCA to total
Ca extrusion is 9%, according to the report by Mackiewicz and Lewartowski, 2006.
- Version:
- $Id: PMCA.java,v 1.1 2006/11/17 08:08:04 atakeuchi Exp $
- Author:
- Ayako Takeuchi
- See Also:
- "Luo and Rudy, Circ Res 74: 1071-1096, 1994"
"Mackiewicz and Lewartowski, J Physiol Pharmacol 57: 3-15, 2006"
Field Summary |
Node |
Cai
concentration of intracellular Ca2+ [mM] |
double |
Cm
membrane capacitance [pF] |
double |
KmCai
dissociation constant for Ca2+ [mM -1 ] |
Node |
permeabilityCa
factor to define the maximum PMCA current [pA/pF] |
Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter |
cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total |
Constructor Summary |
PMCA()
|
Method Summary |
protected void |
calculate(double t)
add Cl current to Compartment.
|
Methods inherited from class org.simBio.core.Component |
addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks |
Methods inherited from class java.lang.Object |
clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait |
Cai
public Node Cai
- concentration of intracellular Ca2+ [mM]
KmCai
public double KmCai
- dissociation constant for Ca2+ [mM -1 ]
permeabilityCa
public Node permeabilityCa
- factor to define the maximum PMCA current [pA/pF]
Cm
public double Cm
- membrane capacitance [pF]
PMCA
public PMCA()
calculate
protected void calculate(double t)
- Description copied from class:
MembraneTransporter
- add Cl current to Compartment.
- Overrides:
calculate
in class MembraneTransporter
- Parameters:
t
- time
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